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Inflammatory Breast Cancer - Diagnosis and Treatment Options

July 29, 2008

by Ray Lam

Inflammatory breast cancer is a special kind of advanced breast cancer and it’s a serious one. Though we see an increasing number of cases, it is rare, accounting for only 1 to 4 percent of all breast cancers. Overall survival is worse in women with this kind of breast cancer than in other forms of breast cancer. It is inflammatory because its initial manifestations are usually redness and warmth in the skin of the breast, often without a palpable lump. Oftentimes, the patient and even the doctor will mistake it for a simple infection and she’ll be put on antibiotics. But it doesn’t get better. It also doesn’t get worse and that’s the tip-off: an infection will always get better or worse within a week or two - it rarely stays the same. If no change seems to be evident, the doctor should perform a biopsy of the underlying tissue to see if it is cancer.

An asymptomatic breast cancer patient was breast-feeding and developed what her doctor thought was lactational mastitis or inflammation of the breast brought about by breast-feeding. It never cleared up and did not hurt much - there was no fever sign of infection. It hadn’t gone away or gotten worse in six months. Another patient, not breast-feeding, noticed that one breast had suddenly become larger than the other; there was also redness and swelling. In both cases, the doctors at first thought the women had breast infections. So if the symptoms continue after treatment, you should ask to have a biopsy done of the breast tissue and of the skin itself. With inflammatory breast cancer, you have cancer in the lymph vessels of your skin, which makes the skin red. An internet survey done on women with the disease by a man whose wife had died of inflammatory breast cancer showed that most women said they wished they had known that when there is redness of the breast skin unresponsive to antibiotic therapy, this is indicative of inflammatory breast cancer. Probably their doctors were not breast specialists and did not know about this unusual type of breast cancer.

It is very easy to mix up the symptoms of inflammatory breast cancer with those of a breast infection. If you become aware of any of the signs of inflammatory breast cancer, see your doctor immediately.

The surgeon may think it is best if the breast is removed and sometimes the breast is removed too early. This early removal of the breast increases the risk of the disease making reappearance.

Patients may not get the specific chemotherapy dose and also the patient may require two treatments of radiation therapy a day rather than only one treatment, as inflammatory breast cancer is a rapid growing cancer. This is where the importance of an experienced radiologist in inflammatory breast cancer is necessary.

There is no particular age at which an individual could get the disease. However, studies have shown that the average age ranges from about 45 and 55 years of age, but patients could be younger or older than this age range. The amount of new cases of inflammatory breast cancer diagnosed every year in the United States varies.

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